Assay
Financial-condition grades for SEC filers
Company Report · as of Oct 9, 2026
|
| Definium Therapeutics, Inc.DFTX · healthcare | |
|---|---|
| Grade |  Astrongest fifth of 371 graded peers; percentile 16.5, sampling error 2.5 points; lower is stronger |
| Rank | 62 of 371 |
| Profitability | Bpercentile 32.0 |
| Solvency | B/Cpercentile 38.9 |
| Growth and financing | B/Cpercentile 40.4 |
| Reliability | 0.87 AUCfailure model, filers with $120M to $591M assets; 95% interval 0.83 to 0.90; 206 events, 2020 to 2025 |
| Peer failure rate | 1.03% a yearItem 1.03 bankruptcies, same asset band, 2012 to 2025 |
| Size band | $120M to $591M assetstotal assets $440.1M[1] |
| Warnings | dilutionnot computable: degenerate inputs, fortress balance sheet |
| Inputs computable | 7 of 14 |
| Graded from | filings received through Feb 26, 2026225 days before the rescan; every figure keyed to the SEC receipt date |
| Last close | $34.172026-10-08; market equity $4.6B; iex feed |
| Price used in grade | None |
| Share price, twelve months to the rescansplit-adjusted close; a lollipop at every rescan carries the letter held then; baseline ticks are SEC receipt dates of the inputs; ranges and dragging scroll the full history | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Percentile at every rescan on file, Jan 21, 2012 to Oct 9, 2026; stronger toward the top. Hover for the date. Open this report as it stood on | ||||||||||||||||||||
Each date opens the report as it stood on that rescan. |
Business, in the company's words. Opening of Item 1 of the 10-K received Feb 26, 2026; the document on sec.gov.
We are a late-stage clinical biopharmaceutical company developing novel product candidates to treat brain health disorders. Our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale. We are developing a pipeline of innovative product candidates targeting neurotransmitter pathways that play key roles in brain health disorders. This specifically includes pharmaceutically optimized product candidates derived from the psychedelic and empathogen drug classes including DT120 (previously referred to as MM120), and DT402 (previously referred to as MM402), our lead product candidates.
Warnings [top]
7 checks ran; none of them enters the letter. The checks are listed on the warnings screen.
The Fourteen Inputs [top]
Lower percentile is stronger. Source numbers open the SEC filing; a range that spans filings opens the sources table.
| Input | Percentile, 0 to 100 | Value | Source | Peer median | Percentile | Peers | Period end |
|---|---|---|---|---|---|---|---|
| Profitability, sleeve percentile 32.0 | |||||||
| Gross profitability | not computable | 32.2% | |||||
| one or more required annual facts are missing | |||||||
| Return on invested capital | not computable | 9.3% | |||||
| one or more required annual facts are missing | |||||||
| Accruals ratio | (14.1%) | [1,4-6] | (6.6%) | 32.0 | 811 | 2025-12-31 | |
| Gross margin stability, five years | not computable | 2.8 pts | |||||
| five annual gross margins are required; found 0 | |||||||
| Solvency, sleeve percentile 38.9 | |||||||
| Twelve-month failure probability | 0.03% | 0.07% | 18.6 | 248 | 2026-06-30 | ||
| Altman Z double-prime | 1.64 | [1,7-12] | (0.31) | 30.1 | 756 | 2025-12-31 | |
| Net debt to EBITDA | not computable | 1.82x | |||||
| one or more required annual facts are missing | |||||||
| Interest coverage | (30.34x) | [10,13] | (4.51x) | 77.5 | 81 | 2025-12-31 | |
| Current ratio | 6.29x | [7-8] | 2.96x | 29.6 | 839 | 2025-12-31 | |
| Growth and financing, sleeve percentile 40.4 | |||||||
| Revenue growth, three-year compound | not computable | 10.0% | |||||
| four annual observations are required; found 0 | |||||||
| Free cash flow growth, three-year compound | not computable | 10.9% | |||||
| four consecutive annual FCF observations are required; found 0 | |||||||
| Reinvestment rate | not computable | 37.1% | |||||
| one or more required annual facts are missing | |||||||
| Asset growth, three years | 37.3% | [1,6,14-15] | 2.1% | 12.1 | 704 | 2025-12-31 | |
| Net share issuance, one year | 32.3% | [2-3] | 2.5% | 68.7 | 634 | 2026-02-19 | |
Gross profitability. Revenue less cost of goods sold, over total assets.
Accruals ratio. Net income less operating cash flow, over average assets; lower is stronger.
Gross margin stability, five years. Standard deviation of gross margin; lower is stronger.
Twelve-month failure probability. CHS model; lower is stronger.
Net debt to EBITDA. Lower is stronger.
Net share issuance, one year. Split-adjusted; lower is stronger.
Sleeves are equal-weighted; within a sleeve each computable input carries equal weight. Composite -0.300; sampling error 2.5 percentile points on 371 peers.
Among 371 Peers [top]
Composite score of every graded peer, smoothed. Vertical rules are the letter band edges at the 20th, 40th, 60th and 80th percentiles. Small dots are the six largest peers by market equity.
| Rank | Company | Percentile | Letter | Warnings |
|---|---|---|---|---|
| 57 | Edwards Lifesciences Corp. (EW) Edwards Lifesciences Corp. (EW) Astrongest fifth; percentile 15.1 NYSE · Orthopedic, Prosthetic & Surgical Appliances & Supplies market equity $48.6B; last close $84.24 No active warnings; 11 of 14 inputs | 15.1 | A | |
| 58 | Vertex Pharmaceuticals Inc. MA (VRTX) Vertex Pharmaceuticals Inc. MA (VRTX) Astrongest fifth; percentile 15.4 Nasdaq · Pharmaceutical Preparations market equity $127.6B; last close $503.17 No active warnings; 11 of 14 inputs | 15.4 | A | |
| 59 | CareDx, Inc. (CDNA) CareDx, Inc. (CDNA) Astrongest fifth; percentile 15.7 Nasdaq · Services-Medical Laboratories market equity $3.2B; last close $62.25 No active warnings; 7 of 14 inputs | 15.7 | A | |
| 60 | Ensign Group, Inc. (ENSG) Ensign Group, Inc. (ENSG) Astrongest fifth; percentile 15.9 Nasdaq · Services-Skilled Nursing Care Facilities market equity $10.0B; last close $171.41 Warnings: fortress balance sheet; 11 of 14 inputs | 15.9 | A | fortress balance sheet |
| 61 | RxSight, Inc. (RXST) RxSight, Inc. (RXST) Astrongest fifth; percentile 16.2 Nasdaq · Ophthalmic Goods market equity $201.7M; last close $4.86 Warnings: fortress balance sheet; 9 of 14 inputs | 16.2 | A | fortress balance sheet |
| 62 | Definium Therapeutics, Inc. (DFTX) Definium Therapeutics, Inc. (DFTX) Astrongest fifth; percentile 16.5 Nasdaq · Medicinal Chemicals & Botanical Products market equity $4.6B; last close $34.17 Warnings: dilution; 7 of 14 inputs | 16.5 | A | dilution |
| 63 | Natures Sunshine Products Inc. (NATR) Natures Sunshine Products Inc. (NATR) Astrongest fifth; percentile 16.8 Nasdaq · Pharmaceutical Preparations market equity $221.2M; last close $12.56 Warnings: fortress balance sheet; 9 of 14 inputs | 16.8 | A | fortress balance sheet |
| 64 | Alnylam Pharmaceuticals, Inc. (ALNY) Alnylam Pharmaceuticals, Inc. (ALNY) Astrongest fifth; percentile 17.0 Nasdaq · Pharmaceutical Preparations market equity $30.0B; last close $224.51 No active warnings; 9 of 14 inputs | 17.0 | A | |
| 65 | Aurinia Pharmaceuticals Inc. (AUPH) Aurinia Pharmaceuticals Inc. (AUPH) Astrongest fifth; percentile 17.3 Nasdaq · Pharmaceutical Preparations market equity $2.2B; last close $16.22 No active warnings; 8 of 14 inputs | 17.3 | A | |
| 66 | Acadia Pharmaceuticals Inc. (ACAD) Acadia Pharmaceuticals Inc. (ACAD) A/Bon the A/B boundary; percentile 17.6 Nasdaq · Pharmaceutical Preparations market equity $3.4B; last close $19.57 No active warnings; 8 of 14 inputs | 17.6 | A/B | |
| 67 | UFP Technologies Inc. (UFPT) UFP Technologies Inc. (UFPT) A/Bon the A/B boundary; percentile 17.8 Nasdaq · Surgical & Medical Instruments & Apparatus market equity $2.2B; last close $287.96 No active warnings; 10 of 14 inputs | 17.8 | A/B |
| Peer policy | Letter | Percentile | Peers |
|---|---|---|---|
| all graded filers, equal sleeves | A | 16.9 | 2204 |
| sector peers, equal sleeves (the grade) | A | 16.5 | 371 |
| same exchange, equal sleeves | A | 18.1 | 1219 |
| sector peers, equal inputs | B | 25.7 | 371 |
Each letter is one fifth of the 371 graded peers, about 74 companies. A boundary letter (A/B, B/C, C/D, D/E) marks a percentile within one sampling error of a band edge.
What the Price Implies [top]
Market measures at the 2026-10-08 close. None enters the grade. Percentile among graded peers with the same measure.
| Measure | Value | Peer median | Percentile | Reading |
|---|---|---|---|---|
| Twelve-month price change, skipping the latest month | 236.9% | 8.0% | 97 | hotter than 97 of 100 peers |
| Distance from 52-week high | (29.5%) | (31.4%) | 53 | closer to its high than 53 of 100 peers |
| EBIT to enterprise value | not computable | (1.5%) | required accounting or market input is missing | |
| Free cash flow yield | not computable | (1.0%) | required accounting or market input is missing | |
| Book value to price | 0.20 | 0.28 | 40 | pricier than 60 of 100 peers |
| Sales to price | not computable | 0.31 | required accounting or market input is missing | |
| Composite equity issuance, five years | not computable | 20.3% | a share count from five years earlier is required | |
| Relative strength against the sector, log excess return | 1.00 | (0.14) | 97 | ahead of 97 of 100 peers |
Inputs: market equity $4.6B; EBIT -$166.3M; book equity $918.7M; cash $655.3M[16].
Diagnostics [top]
Diagnostics do not feed the grade.
| Piotroski F-score: None of 9, period end 2025-12-31 | ||
|---|---|---|
| Return on assets above zero | (60.8%) | ✗ fail[4,6] |
| Operating cash flow above zero | -$131.6M | ✗ fail[5] |
| Return on assets improved | 26.4 pts | ✓ pass[4,6,14,17] |
| Operating cash flow exceeds net income | $52.2M | ✓ pass[4-5] |
| Long-term leverage fell | 0.7 pts | ✗ fail[1,6,14,18-19] |
| Current ratio improved | (96.2 pts) | ✗ fail[7-8,20-21] |
| No new shares issued | 32.3% | ✗ fail[2-3] |
| Gross margin improved | n/a | |
| Asset turnover improved | n/a[6,14] | |
| Cash, filings, liquidity | |
|---|---|
| Cash and equivalents | $655.3M[22] |
| Operating cash flow, four quarters | -$168.0M[5,22-26] |
| Months of runway | 46.8 |
| Late filings, two years | 0 |
| NT 10-K or NT 10-Q | |
| Days since last periodic filing | 64 |
| 10-Q received Aug 6, 2026 | |
| Median daily dollar volume | $75.2M |
| 63 sessions | |
| Days since newest grade input | 225 |
Downloads [top]
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Sources [top]
Every citation on this page. Filing opens the SEC index page for that submission; viewer opens the SEC interactive data for the same filing; series opens the SEC XBRL API record for that tag and company.
| # | Concept | XBRL tag | Value | Period end | Received | Form | Links |
|---|---|---|---|---|---|---|---|
| 1 | assets | us-gaap:Assets | $440.1M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 2 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 99,698,129 | 2026-02-19 | 2026-02-26 | 10-K | filing · viewer · series |
| 3 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 75,368,359 | 2025-02-20 | 2025-03-06 | 10-K | filing · viewer · series |
| 4 | net income | us-gaap:NetIncomeLoss | -$183.8M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 5 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | -$131.6M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 6 | assets | us-gaap:Assets | $302.2M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 7 | current assets | us-gaap:AssetsCurrent | $419.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 8 | current liabilities | us-gaap:LiabilitiesCurrent | $66.7M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 9 | retained earnings | us-gaap:RetainedEarningsAccumulatedDeficit | -$582.7M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 10 | operating income | us-gaap:OperatingIncomeLoss | -$166.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 11 | book equity | us-gaap:StockholdersEquity | $332.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 12 | liabilities | us-gaap:Liabilities | $107.8M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 13 | interest expense | us-gaap:InterestExpense | $5.5M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 14 | assets | us-gaap:Assets | $124.5M | 2023-12-31 | 2025-03-06 | 10-K | filing · viewer · series |
| 15 | assets | us-gaap:Assets | $170.0M | 2022-12-31 | 2024-02-28 | 10-K | filing · viewer · series |
| 16 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 134,366,950 | 2026-07-30 | 2026-08-06 | 10-Q | filing · viewer · series |
| 17 | net income | us-gaap:NetIncomeLoss | -$108.7M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 18 | long term debt | us-gaap:LongTermDebtNoncurrent | $40.6M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 19 | long term debt | us-gaap:LongTermDebtNoncurrent | $21.9M | 2024-12-31 | 2025-03-06 | 10-K | filing · viewer · series |
| 20 | current assets | us-gaap:AssetsCurrent | $281.6M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 21 | current liabilities | us-gaap:LiabilitiesCurrent | $38.8M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 22 | cash | us-gaap:CashAndCashEquivalentsAtCarryingValue | $655.3M | 2026-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
| 23 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | -$95.4M | 2026-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
| 24 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | -$42.6M | 2026-03-31 | 2026-05-07 | 10-Q | filing · viewer · series |
| 25 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | -$88.6M | 2025-09-30 | 2025-11-06 | 10-Q | filing · viewer · series |
| 26 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | -$59.0M | 2025-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
Limitations [top]
Grade boundary. Percentile 16.5 is 3.5 points from the nearest band edge; sampling error is 2.5 points.
Peer group. Sector assignment from four-digit SIC codes, hand-tuned and published. The grade under three alternative peer policies is tabled above.
Size. Within a sector the letter tracks size. Among graded filers in the smallest asset band, 72% grade E and 0% grade A; in the largest, 13% grade E and 21% grade A. Universe as of Oct 9, 2026.
Failure model. filings 2012-01-01 to 2019-12-31 fit, filings 2020-01-01 to 2025-12-31 test; status post hoc pending confirmation. pre-registered on 2026 filings once their 12-month outcome windows close; supported if the paired per-quintile gain over the pooled model has a lower bound above 0.05.
Input validity. Revenue or total assets at or below $100,000 sets the degenerate-inputs flag. An input whose denominator is at or below $100,000 is left not computable rather than ranked.
Returns. No input on this page has a post-2015 confidence interval on returns that excludes zero. The grade ranks reported financial condition and is not a return forecast.
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