Assay

Financial-condition grades for SEC filers

Company Report · as of Oct 9, 2026


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Opko Health, Inc.OPK · healthcare
GradeBearEweakest fifth of 371 graded peers; percentile 84.1, sampling error 2.5 points; lower is stronger
Rank312 of 371
ProfitabilityDpercentile 76.7
SolvencyCpercentile 42.9
Growth and financingDpercentile 67.7
Reliability0.91 AUCfailure model, filers with $591M to $2.67B assets; 95% interval 0.88 to 0.94; 160 events, 2020 to 2025
Peer failure rate1.01% a yearItem 1.03 bankruptcies, same asset band, 2012 to 2025
Size band$591M to $2.67B assetstotal assets $1.9B[1]
Standard universeinsiderevenue above $1M and assets above $10M[1-2]
Warningsnone active · fortress balance sheetnot computable: distress
Inputs computable8 of 14
Graded fromfilings received through Feb 26, 2026225 days before the rescan; every figure keyed to the SEC receipt date
Last close$1.362026-10-08; market equity $1.0B; iex feed
Price used in gradeNone
Share price, twelve months to the rescansplit-adjusted close; a lollipop at every rescan carries the letter held then; baseline ticks are SEC receipt dates of the inputs; ranges and dragging scroll the full history
$1.5NovDecJanFebMarAprMayJunJulAugSepOctD/EE$1.37
ABCDE20132014201520162017201820192020202120222023202420252026

Percentile at every rescan on file, Jan 21, 2012 to Oct 9, 2026; stronger toward the top. Hover for the date.

Open this report as it stood on

Letter setLetterPercentileBand
Jan 21, 2012nonen/a
Mar 21, 2012nonen/aQ3
Mar 21, 2014nonen/aQ4
Mar 21, 2016B33.1Q5
Mar 21, 2017C/D61.9Q5
Mar 21, 2018nonen/aQ4
Feb 21, 2021E87.4Q4
Mar 21, 2022D75.1Q4
Mar 21, 2023E87.5Q4
Feb 21, 2024D/E82.8Q4
Mar 21, 2024D69.6Q4
Mar 21, 2025D/E80.7Q4
Mar 21, 2026E85.5Q4

Each date opens the report as it stood on that rescan.

Business, in the company's words. Opening of Item 1 of the 10-K received Feb 26, 2026; the document on sec.gov.

We are a diversified healthcare company that seeks to establish industry-leading positions in large and rapidly growing medical markets. Our pharmaceutical business features NGENLA® (somatrogon-ghla), also referred to as Somatrogon (hGH-CTP), a once-weekly human growth hormone injection. We have partnered with Pfizer Inc. (“Pfizer”) for further development and commercialization of Somatrogon (hGH-CTP).

Warnings [top]

Fortress balance sheet. cash minus debt is 20,443,000 USD; Altman Z is not used[3-4]

7 checks ran; none of them enters the letter. The checks are listed on the warnings screen.

The Fourteen Inputs [top]

Lower percentile is stronger. Source numbers open the SEC filing; a range that spans filings opens the sources table.

InputPercentile, 0 to 100ValueSourcePeer medianPercentilePeersPeriod end
Profitability, sleeve percentile 76.7
Gross profitability10.7%[1,5]32.2%75.53722025-12-31
Return on invested capital(8.4%)[3-4,6-12]9.3%79.5742025-12-31
Accruals ratio(2.3%)[1,13-15](6.6%)75.28112025-12-31
Gross margin stability, five yearsnot computable2.8 pts
five consecutive annual gross margins are required
Solvency, sleeve percentile 42.9
Twelve-month failure probabilitynot computable0.07%
latest liabilities, cash plus short-term investments, book equity, and shares are required
Altman Z double-prime(0.79)[1,6,9,16-19](0.31)40.07562025-12-31
Net debt to EBITDAnot computable1.82x
EBITDA must exceed $100,000
Interest coveragenot computable(4.51x)
interest expense must exceed $100,000
Current ratio3.97x[16-17]2.96x45.88392025-12-31
Growth and financing, sleeve percentile 67.7
Revenue growth, three-year compound(15.5%)[2,20-22]10.0%87.74152025-12-31
Free cash flow growth, three-year compoundnot computable10.9%
current FCF must be positive and base FCF must exceed $100,000
Reinvestment ratenot computable37.1%
NOPAT must exceed $100,000
Asset growth, three years(3.8%)[1,15,23-24]2.1%60.77042025-12-31
Net share issuance, one year13.0%[25-26]2.5%54.76342026-01-30

Gross profitability. Revenue less cost of goods sold, over total assets.

Accruals ratio. Net income less operating cash flow, over average assets; lower is stronger.

Gross margin stability, five years. Standard deviation of gross margin; lower is stronger.

Twelve-month failure probability. CHS model; lower is stronger.

Net debt to EBITDA. Lower is stronger.

Net share issuance, one year. Split-adjusted; lower is stronger.

Sleeves are equal-weighted; within a sleeve each computable input carries equal weight. Composite 0.263; sampling error 2.5 percentile points on 371 peers.

Among 371 Peers [top]

ABCDEJNJ, Johnson & Johnson; C, percentile 44.9; market equity $618.1BJNJLLY, ELI Lilly & Co.; C, percentile 55.7; market equity $1.1TLLYABBV, AbbVie Inc.; D, percentile 63.2; market equity $481.4BABBVGILD, Gilead Sciences, Inc.; D/E, percentile 78.9; market equity $182.4BGILDMRK, Merck & Co., Inc.; D/E, percentile 80.8; market equity $351.3BMRKAMGN, Amgen Inc.; E, percentile 85.1; market equity $220.3BAMGNOPK 84.1strongerweaker

Composite score of every graded peer, smoothed. Vertical rules are the letter band edges at the 20th, 40th, 60th and 80th percentiles. Small dots are the six largest peers by market equity.

RankCompanyPercentileLetterWarnings
307Stereotaxis, Inc. (STXS)

Stereotaxis, Inc. (STXS)

Eweakest fifth; percentile 82.7

NYSE · Electromedical & Electrotherapeutic Apparatus

market equity $111.2M; last close $1.11

No active warnings; 9 of 14 inputs

82.7E
308SkinHealth Systems Inc. (SKIN)

SkinHealth Systems Inc. (SKIN)

Eweakest fifth; percentile 83.0

Nasdaq · Surgical & Medical Instruments & Apparatus

market equity $74.0M; last close $0.57

No active warnings; 8 of 14 inputs

83.0E
309Karyopharm Therapeutics Inc. (KPTI)

Karyopharm Therapeutics Inc. (KPTI)

Eweakest fifth; percentile 83.2

Nasdaq · Pharmaceutical Preparations

market equity $13.6M; last close $0.60

Warnings: dilution, distress, fortress balance sheet; 7 of 14 inputs

83.2Edilution, distress, fortress balance sheet
310Novavax Inc. (NVAX)

Novavax Inc. (NVAX)

Eweakest fifth; percentile 83.5

Nasdaq · Biological Products, (No Diagnostic Substances)

market equity $1.8B; last close $11.00

No active warnings; 8 of 14 inputs

83.5E
311Pyxis Oncology, Inc. (PYXS)

Pyxis Oncology, Inc. (PYXS)

Eweakest fifth; percentile 83.8

Nasdaq · Pharmaceutical Preparations

market equity $166.0M; last close $1.99

Warnings: short runway, distress; 7 of 14 inputs

83.8Eshort runway, distress
312Opko Health, Inc. (OPK)

Opko Health, Inc. (OPK)

Eweakest fifth; percentile 84.1

Nasdaq · Pharmaceutical Preparations

market equity $1.0B; last close $1.36

Warnings: fortress balance sheet; 8 of 14 inputs

84.1Efortress balance sheet
313Amarin Corp. Plc\Uk (AMRN)

Amarin Corp. Plc\Uk (AMRN)

Eweakest fifth; percentile 84.3

Nasdaq · Pharmaceutical Preparations

market equity $5.0B; last close $12.02

Warnings: fortress balance sheet; 8 of 14 inputs

84.3Efortress balance sheet
314Kalaris Therapeutics, Inc. (KLRS)

Kalaris Therapeutics, Inc. (KLRS)

Eweakest fifth; percentile 84.6

Nasdaq · Biological Products, (No Diagnostic Substances)

market equity $59.5M; last close $2.50

Warnings: dilution; 7 of 14 inputs

84.6Edilution
315Journey Medical Corp. (DERM)

Journey Medical Corp. (DERM)

Eweakest fifth; percentile 84.9

Nasdaq · Pharmaceutical Preparations

market equity $68.8M; last close $5.95

No active warnings; 7 of 14 inputs

84.9E
316Amgen Inc. (AMGN)

Amgen Inc. (AMGN)

Eweakest fifth; percentile 85.1

Nasdaq · Biological Products, (No Diagnostic Substances)

market equity $220.3B; last close $407.41

No active warnings; 11 of 14 inputs

85.1E
317Organon & Co. (OGN)

Organon & Co. (OGN)

Eweakest fifth; percentile 85.4

NYSE · Pharmaceutical Preparations

market equity $3.6B; last close $13.76

No active warnings; 8 of 14 inputs

85.4E
Peer policyLetterPercentilePeers
all graded filers, equal sleevesE91.52204
sector peers, equal sleeves (the grade)E84.1371
same exchange, equal sleevesE86.51219
sector peers, equal inputsE87.8371

Each letter is one fifth of the 371 graded peers, about 74 companies. A boundary letter (A/B, B/C, C/D, D/E) marks a percentile within one sampling error of a band edge.

What the Price Implies [top]

Market measures at the 2026-10-08 close. None enters the grade. Percentile among graded peers with the same measure.

MeasureValuePeer medianPercentileReading
Twelve-month price change, skipping the latest month(5.2%)8.0%43hotter than 43 of 100 peers
Distance from 52-week high(20.8%)(31.4%)64closer to its high than 64 of 100 peers
EBIT to enterprise value(11.0%)(1.5%)32pricier than 68 of 100 peers
Free cash flow yield(18.7%)(1.0%)24pricier than 76 of 100 peers
Book value to price1.160.2889pricier than 11 of 100 peers
Sales to price0.590.3171pricier than 29 of 100 peers
Composite equity issuance, five years10.8%20.3%41more equity-funded than 41 of 100 peers
Relative strength against the sector, log excess return(0.27)(0.14)43ahead of 43 of 100 peers

Inputs: market equity $1.0B; EBIT -$117.4M; free cash flow -$190.8M; book equity $1.2B; sales $606.9M; debt $349.1M; cash $300.8M[27].

Diagnostics [top]

Diagnostics do not feed the grade.

Piotroski F-score: 4 of 9, period end 2025-12-31
Return on assets above zero(10.3%)✗ fail[13,15]
Operating cash flow above zero-$178.5M✗ fail[14]
Return on assets improved(7.6 pts)✗ fail[13,15,23,28]
Operating cash flow exceeds net income$47.1M✓ pass[13-14]
Long-term leverage fell(0.0 pts)✓ pass[1,15,23,29-30]
Current ratio improved53.8 pts✓ pass[16-17,31-32]
No new shares issued13.0%✗ fail[25-26]
Gross margin improved3.3 pts✓ pass[2,5,20,33]
Asset turnover improved(7.9 pts)✗ fail[2,15,20,23]
Cash, filings, liquidity
Cash and equivalents$300.8M[34]
Operating cash flow, four quarters-$123.4M[14,34-38]
Months of runway29.3
Late filings, two years0
NT 10-K or NT 10-Q
Days since last periodic filing74
10-Q received Jul 27, 2026
Median daily dollar volume$3.6M
63 sessions
Days since newest grade input225

Downloads [top]

Sources [top]

Every citation on this page. Filing opens the SEC index page for that submission; viewer opens the SEC interactive data for the same filing; series opens the SEC XBRL API record for that tag and company.

#ConceptXBRL tagValuePeriod endReceivedFormLinks
1assetsus-gaap:Assets$1.9B2025-12-312026-02-2610-Kfiling · viewer · series
2revenueus-gaap:RevenueFromContractWithCustomerExcludingAssessedTax$606.9M2025-12-312026-02-2610-Kfiling · viewer · series
3cashus-gaap:CashAndCashEquivalentsAtCarryingValue$364.4M2025-12-312026-02-2610-Kfiling · viewer · series
4total debtus-gaap:LongTermDebt$344.0M2025-12-312026-02-2610-Kfiling · viewer · series
5gross profitus-gaap:GrossProfit$205.9M2025-12-312026-02-2610-Kfiling · viewer · series
6operating incomeus-gaap:OperatingIncomeLoss-$117.4M2025-12-312026-02-2610-Kfiling · viewer · series
7pretax incomeus-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments-$241.4M2025-12-312026-02-2610-Kfiling · viewer · series
8income taxus-gaap:IncomeTaxExpenseBenefit-$15.7M2025-12-312026-02-2610-Kfiling · viewer · series
9book equityus-gaap:StockholdersEquity$1.3B2025-12-312026-02-2610-Kfiling · viewer · series
10total debtus-gaap:LongTermDebt$437.2M2024-12-312026-02-2610-Kfiling · viewer · series
11book equityus-gaap:StockholdersEquity$1.4B2024-12-312026-02-2610-Kfiling · viewer · series
12cashus-gaap:CashAndCashEquivalentsAtCarryingValue$426.6M2024-12-312026-02-2610-Kfiling · viewer · series
13net incomeus-gaap:NetIncomeLoss-$225.7M2025-12-312026-02-2610-Kfiling · viewer · series
14operating cash flowus-gaap:NetCashProvidedByUsedInOperatingActivities-$178.5M2025-12-312026-02-2610-Kfiling · viewer · series
15assetsus-gaap:Assets$2.2B2024-12-312026-02-2610-Kfiling · viewer · series
16current assetsus-gaap:AssetsCurrent$581.9M2025-12-312026-02-2610-Kfiling · viewer · series
17current liabilitiesus-gaap:LiabilitiesCurrent$146.7M2025-12-312026-02-2610-Kfiling · viewer · series
18retained earningsus-gaap:RetainedEarningsAccumulatedDeficit-$2.3B2025-12-312026-02-2610-Kfiling · viewer · series
19liabilitiesus-gaap:Liabilities$664.0M2025-12-312026-02-2610-Kfiling · viewer · series
20revenueus-gaap:RevenueFromContractWithCustomerExcludingAssessedTax$713.1M2024-12-312026-02-2610-Kfiling · viewer · series
21revenueus-gaap:RevenueFromContractWithCustomerExcludingAssessedTax$863.5M2023-12-312026-02-2610-Kfiling · viewer · series
22revenueus-gaap:RevenueFromContractWithCustomerExcludingAssessedTax$1.0B2022-12-312025-03-0310-Kfiling · viewer · series
23assetsus-gaap:Assets$2.0B2023-12-312025-03-0310-Kfiling · viewer · series
24assetsus-gaap:Assets$2.2B2022-12-312024-03-0110-Kfiling · viewer · series
25shares outstandingdei:EntityCommonStockSharesOutstanding759,067,2562026-01-302026-02-2610-Kfiling · viewer · series
26shares outstandingdei:EntityCommonStockSharesOutstanding671,550,2702025-01-312025-03-2110-K/Afiling · viewer · series
27shares outstandingdei:EntityCommonStockSharesOutstanding746,328,2252026-07-172026-08-2810-Q/Afiling · viewer · series
28net incomeus-gaap:NetIncomeLoss-$53.2M2024-12-312026-02-2610-Kfiling · viewer · series
29long term debtus-gaap:LongTermDebtNoncurrent$2.3M2025-12-312026-02-2610-Kfiling · viewer · series
30long term debtus-gaap:LongTermDebtNoncurrent$3.0M2024-12-312026-02-2610-Kfiling · viewer · series
31current assetsus-gaap:AssetsCurrent$662.1M2024-12-312026-02-2610-Kfiling · viewer · series
32current liabilitiesus-gaap:LiabilitiesCurrent$193.1M2024-12-312026-02-2610-Kfiling · viewer · series
33gross profitus-gaap:GrossProfit$218.5M2024-12-312026-02-2610-Kfiling · viewer · series
34cashus-gaap:CashAndCashEquivalentsAtCarryingValue$300.8M2026-06-302026-08-2810-Q/Afiling · viewer · series
35operating cash flowus-gaap:NetCashProvidedByUsedInOperatingActivities-$62.8M2026-06-302026-08-2810-Q/Afiling · viewer · series
36operating cash flowus-gaap:NetCashProvidedByUsedInOperatingActivities-$19.3M2026-03-312026-08-2810-Q/Afiling · viewer · series
37operating cash flowus-gaap:NetCashProvidedByUsedInOperatingActivities-$152.6M2025-09-302025-10-2910-Qfiling · viewer · series
38operating cash flowus-gaap:NetCashProvidedByUsedInOperatingActivities-$118.0M2025-06-302026-08-2810-Q/Afiling · viewer · series

Limitations [top]

Grade boundary. Percentile 84.1 is 4.1 points from the nearest band edge; sampling error is 2.5 points.

Peer group. Sector assignment from four-digit SIC codes, hand-tuned and published. The grade under three alternative peer policies is tabled above.

Size. Within a sector the letter tracks size. Among graded filers in the smallest asset band, 72% grade E and 0% grade A; in the largest, 13% grade E and 21% grade A. Universe as of Oct 9, 2026.

Failure model. filings 2012-01-01 to 2019-12-31 fit, filings 2020-01-01 to 2025-12-31 test; status post hoc pending confirmation. pre-registered on 2026 filings once their 12-month outcome windows close; supported if the paired per-quintile gain over the pooled model has a lower bound above 0.05.

Input validity. Revenue or total assets at or below $100,000 sets the degenerate-inputs flag. An input whose denominator is at or below $100,000 is left not computable rather than ranked.

Returns. No input on this page has a post-2015 confidence interval on returns that excludes zero. The grade ranks reported financial condition and is not a return forecast.