Assay
Financial-condition grades for SEC filers
Company Report · as of Oct 9, 2026
|
| Puma Biotechnology, Inc.PBYI · healthcare | |
|---|---|
| Grade |  Bsecond fifth of 371 graded peers; percentile 22.7, sampling error 2.5 points; lower is stronger |
| Rank | 85 of 371 |
| Profitability | Bpercentile 24.7 |
| Solvency | B/Cpercentile 42.3 |
| Growth and financing | Cpercentile 48.6 |
| Reliability | 0.87 AUCfailure model, filers with $120M to $591M assets; 95% interval 0.83 to 0.90; 206 events, 2020 to 2025 |
| Peer failure rate | 1.03% a yearItem 1.03 bankruptcies, same asset band, 2012 to 2025 |
| Size band | $120M to $591M assetstotal assets $216.3M[1] |
| Standard universe | insiderevenue above $1M and assets above $10M[1-2] |
| Warnings | none active · fortress balance sheet |
| Inputs computable | 12 of 14 |
| Graded from | filings received through Feb 26, 2026225 days before the rescan; every figure keyed to the SEC receipt date |
| Last close | $9.992026-10-08; market equity $515.7M; iex feed |
| Price used in grade | None |
| Share price, twelve months to the rescansplit-adjusted close; a lollipop at every rescan carries the letter held then; baseline ticks are SEC receipt dates of the inputs; ranges and dragging scroll the full history | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Percentile at every rescan on file, Jan 21, 2012 to Oct 9, 2026; stronger toward the top. Hover for the date. Open this report as it stood on | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Each date opens the report as it stood on that rescan. |
Business, in the company's words. Opening of Item 1 of the 10-K received Feb 26, 2026; the document on sec.gov.
Unless otherwise provided in this Annual Report, references to the “Company,” “we,” “us,” and “our” refer to Puma Biotechnology, Inc. and our wholly owned subsidiary. We are a biopharmaceutical company that develops and commercializes innovative products to enhance cancer care and improve treatment outcomes for patients. We are currently commercializing NERLYNX, an oral version of neratinib, for the treatment of certain HER2-positive breast cancers. Additionally, we have in-licensed, and are responsible for global development and commercialization of, alisertib.
Warnings [top]
7 checks ran; none of them enters the letter. The checks are listed on the warnings screen.
The Fourteen Inputs [top]
Lower percentile is stronger. Source numbers open the SEC filing; a range that spans filings opens the sources table.
| Input | Percentile, 0 to 100 | Value | Source | Peer median | Percentile | Peers | Period end |
|---|---|---|---|---|---|---|---|
| Profitability, sleeve percentile 24.7 | |||||||
| Gross profitability | 78.7% | [1-2,5] | 32.2% | 9.4 | 372 | 2025-12-31 | |
| Return on invested capital | 30.3% | [3-4,6-12] | 9.3% | 8.2 | 74 | 2025-12-31 | |
| Accruals ratio | (5.0%) | [1,13-15] | (6.6%) | 61.4 | 811 | 2025-12-31 | |
| Gross margin stability, five years | 1.3 pts | [2,5,16-23] | 2.8 pts | 19.8 | 243 | 2025-12-31 | |
| Solvency, sleeve percentile 42.3 | |||||||
| Twelve-month failure probability | 0.02% | 0.07% | 3.6 | 248 | 2026-06-30 | ||
| Altman Z double-prime | (14.13) | [1,6,9,24-27] | (0.31) | 68.3 | 756 | 2025-12-31 | |
| Net debt to EBITDA | (0.18x) | [3-4,6,28] | 1.82x | 25.7 | 75 | 2025-12-31 | |
| Interest coverage | not computable | (4.51x) | |||||
| latest aligned inputs end 2023-12-31; latest annual assets end 2025-12-31 | |||||||
| Current ratio | 2.00x | [24-25] | 2.96x | 71.7 | 839 | 2025-12-31 | |
| Growth and financing, sleeve percentile 48.6 | |||||||
| Revenue growth, three-year compound | 0.05% | [2,16,18,20] | 10.0% | 70.8 | 415 | 2025-12-31 | |
| Free cash flow growth, three-year compound | not computable | 10.9% | |||||
| current FCF must be positive and base FCF must exceed $100,000 | |||||||
| Reinvestment rate | 91.1% | [6-8,24-25,28-31] | 37.1% | 35.9 | 104 | 2025-12-31 | |
| Asset growth, three years | (0.9%) | [1,15,32-33] | 2.1% | 52.8 | 704 | 2025-12-31 | |
| Net share issuance, one year | 2.6% | [34-35] | 2.5% | 35.1 | 634 | 2026-02-23 | |
Gross profitability. Revenue less cost of goods sold, over total assets.
Accruals ratio. Net income less operating cash flow, over average assets; lower is stronger.
Gross margin stability, five years. Standard deviation of gross margin; lower is stronger.
Twelve-month failure probability. CHS model; lower is stronger.
Net debt to EBITDA. Lower is stronger.
Net share issuance, one year. Split-adjusted; lower is stronger.
Sleeves are equal-weighted; within a sleeve each computable input carries equal weight. Composite -0.250; sampling error 2.5 percentile points on 371 peers.
Among 371 Peers [top]
Composite score of every graded peer, smoothed. Vertical rules are the letter band edges at the 20th, 40th, 60th and 80th percentiles. Small dots are the six largest peers by market equity.
| Rank | Company | Percentile | Letter | Warnings |
|---|---|---|---|---|
| 80 | Axsome Therapeutics, Inc. (AXSM) Axsome Therapeutics, Inc. (AXSM) A/Bon the A/B boundary; percentile 21.4 Nasdaq · Pharmaceutical Preparations market equity $8.9B; last close $170.26 No active warnings; 7 of 14 inputs | 21.4 | A/B | |
| 81 | Axogen, Inc. (AXGN) Axogen, Inc. (AXGN) A/Bon the A/B boundary; percentile 21.6 Nasdaq · Electromedical & Electrotherapeutic Apparatus market equity $1.9B; last close $36.19 No active warnings; 9 of 14 inputs | 21.6 | A/B | |
| 82 | Halozyme Therapeutics, Inc. (HALO) Halozyme Therapeutics, Inc. (HALO) A/Bon the A/B boundary; percentile 21.9 Nasdaq · Biological Products, (No Diagnostic Substances) market equity $12.5B; last close $109.91 No active warnings; 12 of 14 inputs | 21.9 | A/B | |
| 83 | 4D Molecular Therapeutics, Inc. (FDMT) 4D Molecular Therapeutics, Inc. (FDMT) A/Bon the A/B boundary; percentile 22.2 Nasdaq · Biological Products, (No Diagnostic Substances) market equity $701.2M; last close $12.71 Warnings: dilution, short runway; 7 of 14 inputs | 22.2 | A/B | dilution, short runway |
| 84 | Rhythm Pharmaceuticals, Inc. (RYTM) Rhythm Pharmaceuticals, Inc. (RYTM) A/Bon the A/B boundary; percentile 22.4 Nasdaq · Pharmaceutical Preparations market equity $6.2B; last close $89.61 No active warnings; 9 of 14 inputs | 22.4 | A/B | |
| 85 | Puma Biotechnology, Inc. (PBYI) Puma Biotechnology, Inc. (PBYI) Bsecond fifth; percentile 22.7 Nasdaq · Pharmaceutical Preparations market equity $514.7M; last close $9.99 Warnings: fortress balance sheet; 12 of 14 inputs | 22.7 | B | fortress balance sheet |
| 86 | Warby Parker Inc. (WRBY) Warby Parker Inc. (WRBY) Bsecond fifth; percentile 23.0 NYSE · Ophthalmic Goods market equity $2.8B; last close $24.96 No active warnings; 7 of 14 inputs | 23.0 | B | |
| 87 | Cronos Group Inc. (CRON) Cronos Group Inc. (CRON) Bsecond fifth; percentile 23.2 Nasdaq · Medicinal Chemicals & Botanical Products market equity $1.2B; last close $3.23 No active warnings; 9 of 14 inputs | 23.2 | B | |
| 88 | Guardant Health, Inc. (GH) Guardant Health, Inc. (GH) Bsecond fifth; percentile 23.5 Nasdaq · Services-Medical Laboratories market equity $22.2B; last close $165.62 No active warnings; 7 of 14 inputs | 23.5 | B | |
| 89 | Avalo Therapeutics, Inc. (AVTX) Avalo Therapeutics, Inc. (AVTX) Bsecond fifth; percentile 23.8 Nasdaq · Pharmaceutical Preparations market equity $720.3M; last close $13.43 Warnings: dilution, degenerate inputs; 7 of 14 inputs | 23.8 | B | dilution, degenerate inputs |
| 90 | Sarepta Therapeutics, Inc. (SRPT) Sarepta Therapeutics, Inc. (SRPT) Bsecond fifth; percentile 24.1 Nasdaq · Pharmaceutical Preparations market equity $1.9B; last close $18.22 No active warnings; 9 of 14 inputs | 24.1 | B |
| Peer policy | Letter | Percentile | Peers |
|---|---|---|---|
| all graded filers, equal sleeves | A/B | 19.2 | 2204 |
| sector peers, equal sleeves (the grade) | B | 22.7 | 371 |
| same exchange, equal sleeves | A | 17.9 | 1219 |
| sector peers, equal inputs | B | 22.7 | 371 |
Each letter is one fifth of the 371 graded peers, about 74 companies. A boundary letter (A/B, B/C, C/D, D/E) marks a percentile within one sampling error of a band edge.
What the Price Implies [top]
Market measures at the 2026-10-08 close. None enters the grade. Percentile among graded peers with the same measure.
| Measure | Value | Peer median | Percentile | Reading |
|---|---|---|---|---|
| Twelve-month price change, skipping the latest month | 71.6% | 8.0% | 83 | hotter than 83 of 100 peers |
| Distance from 52-week high | 0.0% | (31.4%) | 98 | closer to its high than 98 of 100 peers |
| EBIT to enterprise value | 7.6% | (1.5%) | 86 | pricier than 14 of 100 peers |
| Free cash flow yield | 8.1% | (1.0%) | 88 | pricier than 12 of 100 peers |
| Book value to price | 0.27 | 0.28 | 49 | pricier than 51 of 100 peers |
| Sales to price | 0.44 | 0.31 | 63 | pricier than 37 of 100 peers |
| Composite equity issuance, five years | 24.9% | 20.3% | 53 | more equity-funded than 53 of 100 peers |
| Relative strength against the sector, log excess return | 0.33 | (0.14) | 83 | ahead of 83 of 100 peers |
Inputs: market equity $514.7M; EBIT $37.3M; free cash flow $41.7M; book equity $138.5M; sales $228.4M; debt $11.3M; cash $36.5M[36].
Diagnostics [top]
Diagnostics do not feed the grade.
| Piotroski F-score: 8 of 9, period end 2025-12-31 | ||
|---|---|---|
| Return on assets above zero | 14.6% | ✓ pass[13,15] |
| Operating cash flow above zero | $41.8M | ✓ pass[14] |
| Return on assets improved | 1.4 pts | ✓ pass[13,15,32,37] |
| Operating cash flow exceeds net income | $10.7M | ✓ pass[13-14] |
| Long-term leverage fell | (9.8 pts) | ✓ pass[1,15,32,38-39] |
| Current ratio improved | 46.6 pts | ✓ pass[24-25,30-31] |
| No new shares issued | 2.6% | ✗ fail[34-35] |
| Gross margin improved | 2.5 pts | ✓ pass[2,5,16-17] |
| Asset turnover improved | 7.1 pts | ✓ pass[2,15-16,32] |
| Cash, filings, liquidity | |
|---|---|
| Cash and equivalents | $36.5M[40] |
| Operating cash flow, four quarters | $41.1M[14,40-44] |
| Months of runway | not finite |
| trailing operating cash flow is nonnegative, so runway is not finite | |
| Late filings, two years | 0 |
| NT 10-K or NT 10-Q | |
| Days since last periodic filing | 64 |
| 10-Q received Aug 6, 2026 | |
| Median daily dollar volume | $2.6M |
| 63 sessions | |
| Days since newest grade input | 225 |
Downloads [top]
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Sources [top]
Every citation on this page. Filing opens the SEC index page for that submission; viewer opens the SEC interactive data for the same filing; series opens the SEC XBRL API record for that tag and company.
| # | Concept | XBRL tag | Value | Period end | Received | Form | Links |
|---|---|---|---|---|---|---|---|
| 1 | assets | us-gaap:Assets | $216.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 2 | revenue | us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax | $228.4M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 3 | cash | us-gaap:CashAndCashEquivalentsAtCarryingValue | $29.6M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 4 | total debt | us-gaap:LongTermDebt | $22.7M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 5 | cost of revenue | us-gaap:CostOfGoodsAndServicesSold | $58.2M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 6 | operating income | us-gaap:OperatingIncomeLoss | $37.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 7 | pretax income | us-gaap:IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest | $35.8M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 8 | income tax | us-gaap:IncomeTaxExpenseBenefit | $4.7M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 9 | book equity | us-gaap:StockholdersEquity | $130.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 10 | total debt | us-gaap:LongTermDebt | $68.0M | 2024-12-31 | 2025-02-27 | 10-K | filing · viewer · series |
| 11 | book equity | us-gaap:StockholdersEquity | $92.1M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 12 | cash | us-gaap:CashAndCashEquivalentsAtCarryingValue | $69.2M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 13 | net income | us-gaap:NetIncomeLoss | $31.1M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 14 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | $41.8M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 15 | assets | us-gaap:Assets | $213.3M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 16 | revenue | us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax | $230.5M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 17 | cost of revenue | us-gaap:CostOfGoodsAndServicesSold | $64.4M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 18 | revenue | us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax | $235.6M | 2023-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 19 | cost of revenue | us-gaap:CostOfGoodsAndServicesSold | $62.7M | 2023-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 20 | revenue | us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax | $228.0M | 2022-12-31 | 2025-02-27 | 10-K | filing · viewer · series |
| 21 | cost of revenue | us-gaap:CostOfGoodsAndServicesSold | $55.1M | 2022-12-31 | 2025-02-27 | 10-K | filing · viewer · series |
| 22 | revenue | us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax | $253.2M | 2021-12-31 | 2024-02-29 | 10-K | filing · viewer · series |
| 23 | cost of revenue | us-gaap:CostOfGoodsAndServicesSold | $63.7M | 2021-12-31 | 2024-02-29 | 10-K | filing · viewer · series |
| 24 | current assets | us-gaap:AssetsCurrent | $162.7M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 25 | current liabilities | us-gaap:LiabilitiesCurrent | $81.3M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 26 | retained earnings | us-gaap:RetainedEarningsAccumulatedDeficit | -$1.3B | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 27 | liabilities | us-gaap:Liabilities | $86.0M | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 28 | depreciation amortization | us-gaap:Depreciation | $400,000 | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 29 | capital expenditure | us-gaap:PaymentsToAcquirePropertyPlantAndEquipment | $71,000 | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 30 | current assets | us-gaap:AssetsCurrent | $147.7M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 31 | current liabilities | us-gaap:LiabilitiesCurrent | $96.1M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 32 | assets | us-gaap:Assets | $230.5M | 2023-12-31 | 2025-02-27 | 10-K | filing · viewer · series |
| 33 | assets | us-gaap:Assets | $222.1M | 2022-12-31 | 2024-02-29 | 10-K | filing · viewer · series |
| 34 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 50,876,487 | 2026-02-23 | 2026-02-26 | 10-K | filing · viewer · series |
| 35 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 49,610,799 | 2025-02-24 | 2025-02-27 | 10-K | filing · viewer · series |
| 36 | shares outstanding | dei:EntityCommonStockSharesOutstanding | 51,620,066 | 2026-08-03 | 2026-08-06 | 10-Q | filing · viewer · series |
| 37 | net income | us-gaap:NetIncomeLoss | $30.3M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 38 | long term debt | us-gaap:LongTermDebtNoncurrent | $0 | 2025-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 39 | long term debt | us-gaap:LongTermDebtNoncurrent | $21.7M | 2024-12-31 | 2026-02-26 | 10-K | filing · viewer · series |
| 40 | cash | us-gaap:CashAndCashEquivalentsAtCarryingValue | $36.5M | 2026-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
| 41 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | $17.0M | 2026-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
| 42 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | $15.4M | 2026-03-31 | 2026-05-07 | 10-Q | filing · viewer · series |
| 43 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | $27.4M | 2025-09-30 | 2025-11-06 | 10-Q | filing · viewer · series |
| 44 | operating cash flow | us-gaap:NetCashProvidedByUsedInOperatingActivities | $17.7M | 2025-06-30 | 2026-08-06 | 10-Q | filing · viewer · series |
Limitations [top]
Grade boundary. Percentile 22.7 is 2.7 points from the nearest band edge; sampling error is 2.5 points.
Peer group. Sector assignment from four-digit SIC codes, hand-tuned and published. The grade under three alternative peer policies is tabled above.
Size. Within a sector the letter tracks size. Among graded filers in the smallest asset band, 72% grade E and 0% grade A; in the largest, 13% grade E and 21% grade A. Universe as of Oct 9, 2026.
Failure model. filings 2012-01-01 to 2019-12-31 fit, filings 2020-01-01 to 2025-12-31 test; status post hoc pending confirmation. pre-registered on 2026 filings once their 12-month outcome windows close; supported if the paired per-quintile gain over the pooled model has a lower bound above 0.05.
Input validity. Revenue or total assets at or below $100,000 sets the degenerate-inputs flag. An input whose denominator is at or below $100,000 is left not computable rather than ranked.
Returns. No input on this page has a post-2015 confidence interval on returns that excludes zero. The grade ranks reported financial condition and is not a return forecast.
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